Evolução e Ecologia de Microrganismos

Interesse da Investigação

Our group is doing research mostly in evolutionary ecology of microorganisms, with a focus on bacteria, viruses and plasmids. Our approach involves both laboratory work and theoretical research. We study cooperation, competition, spite, and sex among bacterial cells, and their impact on pathogenicity and antibiotic resistance.

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Publicações

(selected) Updated February (2012).

Gama, J.A., Abby, S.S., Vieira-Silva, S., Dionisio, F., Rocha, E.P.C. (2012). Immune Subversion and Quorum-Sensing Shape the Variation in Infectious Dose among Bacterial Pathogens. doi:10.1371/journal.ppat.1002503 PLoS Pathog 8(2) :e1002503

Silva, R.F., Mendonça, S.C.M., Carvalho, L.M., Reis, A.M., Gordo, I., Trindade, S., Dionisio, F. (2011). Pervasive Sign Epistasis between Conjugative Plasmids and Drug-Resistance Chromosomal Mutations. doi:10.1371/journal.pgen.1002181 PLoS Genetics 7(7) :e1002181

Trindade, S., Sousa, A., Xavier, K., Dionisio, F., Ferreira, M.G. and Isabel Gordo (2009). Positive Epistasis Drives the Acquisition of Multidrug Resistance PLoS Genet 5(7) :e1000578

Nogueira, T., Rankin, D.J., Touchon, M., Taddei, F., Brown, S.P., Rocha, E.P.C. (2009). Horizontal Gene Transfer of the Secretome Drives the Evolution of Bacterial Cooperation and Virulence Current Biology 19 (20) :1683-1691

Dionisio, F., Gordo, I. (2007). Controlling excludability in the evolution of cooperation Evolutionary Ecology Research 9(2) :365-373

Dionisio, F. (2007). Selfish and spiteful behaviour through parasites and pathogens Evolutionary Ecology Research 9 :1199-1210

Dionisio, F., Gordo, I. (2006). The Tragedy of the Commons, the Public Goods Dilemma, and the meaning of Rivalry and Excludability in Evolutionary Biology. Evolutionary Ecology Research 8 :321-332

Dionisio, F. (2005). Plasmids survive despite their cost and male-specific-phages due to heterogeneity of bacterial populations Evolutionary Ecology Research 7 :1089-1107

Dionisio, F., Conceição, I.C., Marques A.C.R., Fernandes, L. and Gordo, I. (2005). The evolution of a conjugative plasmid and its ability to increase bacterial fitness Biol. Lett. 1 :250-252

Dionisio, F., Matic, I., Radman, M., Rodrigues, O. R., Taddei, F. (2002). Plasmids spread faste in heterogeneous bacterial communities. Genetics 162(4) :1525-1532

Vulic, M., Dionisio, F. et al. (1997). Molecular Keys to Speciation: DNA Polymorphism and the Control of Genetic Exchange in Enterobacteria. Proc Natl Acad Sci 94 :9763-9767