Morfogénese

Interesse da Investigação

Cell and Developmental Biology, Morphogenesis, Cell Adhesion, Wound Healing, Dorsal Closure, Drosophila Genetics.

Publicações

Jacinto, A. and Baum, B. (2003). Actin in Development. Mech Dev 120 :1337-1349

Wood, W. and Jacinto, A. (2003). Imaging cell movement during dorsal closure in Drosophila embryos, in Cell Migration in Development - Methods in Molecular Biology (Guan, J.L., ed.), Humana press, in press.

Jacinto, A., Woolner, S. and Martin P. (2002). Dynamic analysis of dorsal closure in Drosophila – from genetics to cell biology. Dev Cell 3 :9-19

Jacinto, A., Wood, W., Woolner, S., Hiley, C., Turner, L., Wilson, C., Martinez-Arias, A. and Martin P. (2002). Dynamic analysis of actin cable function during Drosophila dorsal closure. Curr Biol 12 :1245-1250

Wood, W., Jacinto, A., Grose, R., Gale, J., Wilson, C. and Martin, P. (2002). Wound healing recapitulates morphogenesis , co-ordinated regulation of actin cytoskeletal elements by small GTPases during repair of epithelial wounds in Drosophila embryos. Nat Cell Biol 4 :907-912

Kaltschmidt, J., Lawrence, N., Morel, V., Balayo, T., Garcia-Fernandez, B., Pelissier, A., Jacinto, A. and Martinez-Arias, A. (2002). Planar polarity and actin dynamics in the epidermis of Drosophila. Nat Cell Biol 4 :937-944

Jacinto A., Martinez-Arias A., Martin P. (2001). Mechanisms of epithelial fusion and repair. Nat Cell Biol 3 :E117-23

Jacinto, A., Wood, W., Balayo, T., Turmaine, M., Martinez-Arias, A., Martin, P. (2000). Dynamic actin-based epithelial adhesion and cell matching during Drosophila dorsal closure. Curr Biol 10 :1420-1426

Alexandre, C., Jacinto, A. and Ingham, P.W. (1996). Transcriptional activation of hedgehog target genes in Drosophila is mediated by the Cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins. Genes & Dev. 10 :2003-2013

Fietz, M.I., Jacinto, A., Taylor, A.M., Alexandre, C. and Ingham, P.W. (1995). Secretion of the amino-terminal fragment of the Hedgehog protein is necessary and sufficient for hedgehog signaling in Drosophila. Curr. Biol. 5 :643-650